Engine failure at 78,172, excess wear to the camshaft lobes and valve tappet surface. We have had 22 failures. There was a recall -24B27 for 2021 and 2022 models year for idle oil pressure. Most vans had 70 to 80k on them by the time we received a letter. Some engine have been…

11/28/2025 · NHTSA ODI #11701901.0

2021 E-350 · steering

After hitting a very rough patch of interstate, our steering became very difficult. The driver thought that maybe we had a low tire, so looked for a place to pull over. We crested a hill, and there was an exit with a truck stop. As we attempted to slow for the exit, the…

08/18/2024 · NHTSA ODI #11609275.0

2021 E-350 · other

The vehicle was very difficult to keep on the road. It wanted to go all over the road. It was a struggle to keep it in the lane. We took the RV back to the dealer we bought it from & they told us they didn't work on that & to find a Ford dealer that would work on it. After many…

08/04/2021 · NHTSA ODI #11427787.0

2021 E-350 · steering

The contact owns a 2021 Ford E-350. The contact stated while driving 60 mph, the contact started to smell a burning odor coming from the RV. The contact attempted to pull over the RV to the side of the roadway however, the RV became difficult to steer. The contact pulled over…

07/13/2021 · NHTSA ODI #11424629.0

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Active recalls showing 3 of 4

severe NHTSA 20V175000 23/03/2020

Ford Motor Company (Ford) is recalling certain 2021 E-350 and E-450 vehicles

Damage to the fuel pump circuit in the wiring harness could result in an unexpected engine stall. Damage to the ABS wiring can lead to reduction of ABS functionality and a loss of roll stability control (RSC) functionality. These scenarios increase the risk of a crash.

Fix: Ford will notify owners, and dealers will inspect the wire harness for damage. If no damage is found, dealers will apply anti-abrasion tape over the area and ensure clearance to surrounding components. If damage is found, dealers will splice in new wire and apply anti-abrasion tape over the area and ensure clearance to surrounding components. All services will be performed free of charge. The recall began May 18, 2020. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 20S13.

severe NHTSA 20V099000 21/02/2020

Ford Motor Company (Ford) is recalling certain 2020 F-550 and 2021 E-350 and E-450 vehicles

If the driveshaft separates, there may be a loss of drive, increasing the risk of crash. Additionally, if the parking brake is not applied, unintended vehicle movement can occur and increase the risk of injury or crash.

Fix: Ford will notify owners, and dealers will inspect the rear axle differential fluid level and adjust it, or replace the rear axle as necessary, free of charge. The recall began March 19, 2020. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 20S09.

severe NHTSA 20V795000 17/12/2020

Ford Motor Company (Ford) is recalling certain 2021 E-350 and E-450 vehicles

Direct and continuous contact with certain areas of engine cover surface in the passenger compartment may increase the risk of injury or burns to the skin of the driver or front seat passenger.

Fix: Ford will notify owners, and dealers will inspect the engine cover for gaps between the rubber seal and the insulation. If gaps are present, the dealer will install engine cover insulation patches in the right hand and left hand inner lower corners of the engine cover. The dealer will also update the powertrain calibration for heat management under elevated idle conditions should a vehicle be equipped with SEIC or BCP, free of charge. The recall began February 15, 2021. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 20S73.

View all 4 recalls →

Common questions

Is the 2021 Ford E-350 reliable?

Mostly yes. With a reliability score of 7.8 out of 10 based on 20 owner complaints filed with NHTSA, the 2021 Ford E-350 is generally a sound vehicle. The areas to watch are listed in the top problem section above — most are budget items, not deal-breakers.

What's the most common problem on the 2021 Ford E-350?

Based on NHTSA records, the most-reported issue is engine, with 9 complaints filed. Average repair cost runs about $3,100 at an independent shop.

What's the most expensive thing that goes wrong?

The engine is one of the costlier repair items. Average repair cost runs about $3,100 at an independent shop. Catching early warning signs can sometimes extend life by 20–30,000 miles.

How do I check if my Ford E-350 has open recalls?

Paste your VIN into the decoder at the top of this page. We pull live from NHTSA, so you'll see exactly which campaigns apply to your vehicle and whether the dealer has logged the fix. Recall repairs are always free regardless of mileage or warranty status.

Is an extended warranty worth it on a 2021 Ford E-350?

Math is straightforward: a quality service contract runs $1,800–3,500 over 3 years. With 20 complaints on file and the costliest repair averaging $3,100, one major failure more than pays for it. The catch is reading the contract — many providers exclude wear items and require pre-authorization, so cheaper plans aren't always better value.

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Recall and complaint data sourced from the National Highway Traffic Safety Administration (NHTSA) public records database, last synced 19 hours ago. Editorial commentary written by ProblemsByVin contributors and reviewed by ASE-certified mechanics. We are not affiliated with ford. Some links on this page are affiliate links and we may earn a commission if you complete a quote or purchase.