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2021 ford E-350 engine problems
moderate 9 complaints filed with NHTSA
· avg repair $3,100
Complaints
9
Recalls
2
Crashes
0
Avg fix
$3,100
Related recalls
severeNHTSA 20V79500017/12/2020
Ford Motor Company (Ford) is recalling certain 2021 E-350 and E-450 vehicles
Direct and continuous contact with certain areas of engine cover surface in the passenger compartment may increase the risk of injury or burns to the skin of the driver or front seat passenger.
Fix: Ford will notify owners, and dealers will inspect the engine cover for gaps between the rubber seal and the insulation. If gaps are present, the dealer will install engine cover insulation patches in the right hand and left hand inner lower corners of the engine cover. The dealer will also update the powertrain calibration for heat management under elevated idle conditions should a vehicle be equipped with SEIC or BCP, free of charge. The recall began February 15, 2021. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 20S73.
severeNHTSA 25V79300017/11/2025
Ford Motor Company (Ford) is recalling certain 2021 E-350 and E-450 vehicles that received an incomplete software update under recall 20V795
Direct contact with certain areas of engine cover surface in the passenger compartment may increase the risk of injury or burns to the skin of the driver or front seat passenger.
Fix: Dealers will update the powertrain calibration for heat management under elevated idle conditions, free of charge. Owner notification letters were mailed January 7, 2026. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 25SC7. Vehicle Identification Numbers (VINs) involved in this recall will be searchable on NHTSA.gov beginning December 22, 2025.
What owners are reporting
9 most recent
engine
· filed 11/28/2025
Engine failure at 78,172, excess wear to the camshaft lobes and valve tappet surface. We have had 22 failures. There was a recall -24B27 for 2021 and 2022 models year for idle oil pressure. Most vans had 70 to 80k on them by the time we received a letter. Some engine have been changed twice. Ford has a serious problem and is not acknowledging it. Please help! Montachusett Regional Transit Author…
engine
· filed 06/21/2021
The contact owns a 2021 FORD E-350. The contact received notification of NHTSA Campaign Number: 20V795000 (ENGINE) however, the dealer informed the contact that only one part of the remedy, mentioned on the manufacturer's website, was available and not the other. The contact received the reprogramming (UPDATE THE POWERTRAIN CALIBRATION) mentioned on the Ford website but not the other portion of t…
engine
· filed 04/12/2024
See attached document for complaint,
engine
· filed 04/12/2024
See attached document for complaint,
engine
· filed 04/12/2024
See attached document for complaint,
engine
· filed 02/17/2025
This is one of 4 of my 2021 ford econoline fleet vehicles purchased in 2021 that have had engine failure. I am one of many contractors in my area and others around the country who have had this issue with the same F59 engine. Ford has failed to issue a recall.
engine
· filed 02/17/2025
This is one of 4 of my 2021 ford econoline fleet vehicles purchased in 2021 that have had engine failure. I am one of many contractors in my area and others around the country who have had this issue with the same F59 engine. Ford has failed to issue a recall.
engine
· filed 02/17/2025
This is one of 4 of my 2021 ford econoline fleet vehicles purchased in 2021 that have had engine failure. I am one of many contractors in my area and others around the country who have had this issue with the same F59 engine. Ford has failed to issue a recall.
engine
· filed 01/31/2026
fatal Camshaft and lifter failure requiring an engine replacement
Common questions
How serious is the engine problem on the 2021 ford E-350?
It's a documented issue but not catastrophic. 9 complaints have been filed. Repairs average $3,100 and most owners catch it before it causes a breakdown.
At what mileage does the engine typically fail?
Mileage data is limited for this issue. Owners report failures across a wide range, suggesting cause is more about driving conditions and maintenance than mileage alone.
What does it cost to fix?
Independent shops typically charge around $3,100 for engine repairs on this vehicle. Dealer pricing tends to run 20-40% higher. The exact figure depends on the specific failure mode, parts availability, and your local labor rates. If you're outside factory warranty, an extended service contract often covers this category.
Are there any recalls related to engine?
Yes — 2 active recall(s) cover engine issues on this vehicle. Recall fixes are always free regardless of mileage or warranty status. Use the VIN decoder at the top of the page to check if your specific vehicle is affected.
Complaint and recall data sourced from the National Highway Traffic Safety Administration (NHTSA)
public records database. Severity ratings are derived from reported crashes, fires, injuries, and fatalities.
Repair cost estimates are independent-shop national averages and may differ in your area.
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